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is worthy of note that his appearance was attributed by his medical attendants, as well as by his friends, to jaundice ; with a view to cure which the latter performed several superstitious rites with great assiduity, one of which consisted in the daily evaporation of a portion of urine. As soon as a month after his first attack his complexion, from being quite fair, was noticed to have become darker, and his face was of a dirty yellow colour. This increased in intensity as the end of life approached. During the last week he vomited constantly all he took, and was much troubled with hiccough, became gradually weaker, and died quietly and rather unexpectedly. During the last two days he had anæsthesia of feet and partly of legs, with pain in toes and fingers. From these symptoms I was led to diagnose Addison’s disease.

Post-mortem, eighteen hours after death.- Rigor mortis well marked. Almost the entire surface of the body, with the exception of the upper portion of the chest, which was of an ordinary flesh colour, was of a dusky olive hue. The face, hands, amd legs, were the darkest ; but the back, outside of thighs and buttocks, were of a most decided tawny colour ; on the face there were patches of a brown colour, and on the front of both knees, and along the course of the spine in the dorsal region, were others of two or three inches in extent of a very dark brown. The scrotum was much discoloured, almost black, a change of comparatively recent date, and the penis also, but to a lesser degree. The boy had quite the appearance of a mulatto. The conjunctivæ were quite white and pearly. There was no opportunity of examining the urine, but the amount excreted for the last few days was but small. Body not much wasted. The left supra-renal capsule was rather larger than usual, and much altered in character, the distinctions between the various portions quite obliterated. The stroma was pale and flabby, and in it were numerous patches of a firm light-yellowish material, having the look of strumous deposits, one nearly as large as a hazel nut. The right capsule was about its normal size, and studded with yellow spots similar to those of its fellow, but not so large - the deposits being evidently of the same nature, but of longer duration, and undergoing degeneration. The mesenteric glands were enlarged, but not to any great size. There existed some fine pleuritic adhesions on the right side, but the pulmonary tissue of both lungs was positively healthy, and neither in the kidneys nor elsewhere was there any trace of disease.

The lad’s father died of phthisis pulmonalis, as had also other relatives.

The early age at which the disease occurred in this case is worthy of notice.