80.
Dr. WILKS, Guy’s Hosp. Reports, vol. viii., p. 34, Drs. VINCENT and RANKING, Norwich.

Female, 59.

Married lady, affluent, mother of five children, of active habits, but very stout. Discoloration about one year; illness, eight months.

Complete loss of appetite; constant sickness; irritability of body and mind; feeble pulse; faintness; rallied once, but colour continues to deepen; muttering delirium last day of life.

Face and hands first discoloured - later, general surface, but less markedly under dress; face, neck, and hands of a dirty copper colour; peculiar sickening smell from skin about neck; conjunctivæ clear.

Both enlarged, nodulated, and composed of two substances in about equal quantity - one firm, smooth on section, of a dull-green colour, the other yellow and more friable; under microscope, material appeared to be degenerated lymph.

Lungs and other organs healthy; skin loaded with yellow fat.

81.
Dr. WILKS, Guy’s Hosp. Reports, vol. viii., p. 59, Mr. STEDMAN, Godalming.

Male, 32, agricultural labourer.

Had been healthy. Illness, four years.

At first, vomiting and purging; afterwards lassitude, sense of sinking in abdomen, flatulence, and sickness, which became constant, with total prostration two days before death.

Face mulatto-coloured; back and thighs darker; penis and scrotum as dark as those of a negro; conjunctivæ pearly white.

Right capsule absent; left one large, hard, and nodulated, shewing on section a tough albumino-fibrous substance, which enclosed opaque friable matter containing some chalky grains.

All healthy; no emaciation; thick layer of fat lining abdominal parietes.

82.
Dr. HABERSHON, Guy’s Hosp. Reports, vol. x., p. 80, Mr. WEBB.

Female, 19.

None given. Ailing two and a-half years; illness, six months.

Slight pain in stomach; sickness and progressive weakness; amenorrhea six months; pulse feeble and compressible; three days before death, seized with pain in head, followed by drowsiness and insensibility; died comatose.

Skin resembling that of a mulatto, some parts of body being almost as dark as that of a negro; deposit of pigment in gums.

Left capsule consisted only of a mass of white, low-organised product, surrounded by dense tissue; fatty and semi-cretaceous substance replaced the normal structure; under microscope, fibroid tissue, imperfect cell-growth, and highly refracting granules were

Lungs and other organs normal; body plump.